The value of real-world evidence to oncologists

A new landscape of research on cancer Improvements in oncology are usually mainly due to the results of controlled clinical trials that try to replicate clinical practice in a context in which trial investigators attempt to avoid the risks of bias by rigidly controlling most of the potentially interfering variables. However, it is clear that this is very different from real clinical practice, which is characterized by a countless number of variables that can affect the efficacy and tolerability of an individual drug. There may be more similarities in the case of very broad patient selection criteria, but most clinical...