The role of colorectal cancer plasticity in metastasis and treatment: an interview with Mirjana Efremova

In this interview, Mirjana Efremova (Medical University of Innsbruck, Austria) speaks to Megan Bryant, Journal Development Editor for Colorectal Cancer at the 4th International Cancer Conference at the CRICK Institute about her research into how colorectal cells adapt and change through plasticity. Could you explain how cancer cell plasticity plays a role in the metastasis of colorectal cancer cells & their resistance to therapy? In our research so far, we have identified putative pro-metastatic cells in colorectal cancer patient samples that we think are the cells that disseminate and metastasize in the liver. We also have uncovered gene regulatory networks that...