Imagine a scenario where an oncologist sits in a consultation room with their patient, reviews the results of molecular profiling of their patient’s tumor, and then utilize these data to select the most appropriate clinical trial from a menu of hundreds of trials that can be offered, right there, within their office. Somewhat ironically, it is not the former aspect of this scenario, the molecular profiling, that seems like science fiction – this is occurring in oncologists’ offices throughout the world. Rather, it is the ability of any oncologist to offer their patients convenient access to virtually any clinical trial that seems wildly unrealistic. While the science of oncology has progressed at breakneck speed, the conduct of clinical trials has remained “business as usual” for decades.
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