Could clarifying clinical trial concepts increase patient participation?
A nationwide study across Ireland revealed that the vast majority of patients do not understand the core concepts underpinning a clinical trial.
Browsing: Clinical trials
Discover overall survival data from the ENDEAVOR trial: an interview with Meletios A. Dimopoulos
We spoke with a key study investigator of the multiple myeloma ENDEAVOR trial to explore the trial in more detail and to discover the potential clinical application of its overall survival findings.
ESMO 2017: Durvalumab improves progression free survival in stage III lung cancer
A recent clinical trial presents new data indicating durvalumab improves progression-free survival in patients with stage III non-small-cell lung cancer (NSCLC).
Short peptides interfering with signaling pathways as new therapeutic tools for cancer treatment
This review reports the results of application of short peptides in glioma therapy clinical trials, their rises and falls.
Trisenox: a paradigm shift in APL therapy, an interview with Francesco Lo-Coco
In this interview with Francesco Lo-coco we discussed a randomized clinical trial conducted with the drug Trisenox as well as, the genetic characterization, monitoring and treatment of hematologic tumors, particularly acute promyelocytic leukemia.
Future prospects of therapeutic clinical trials in acute myeloid leukemia
What are the current limitation with clinical trials for AML? This review discusses trial end points, patient enrollment, cost of drug discovery and patient heterogeneity and future treatment of AML.
Current clinical trials for melanoma vaccines: where do we stand?
In this editorial from Melanoma Management the authors examine melanoma clinical trials with a focus upon targeted therapies and melanoma vaccines.
Potential therapeutic target discovered for diffuse intrinsic pontine glioma
Researchers have identified a novel potential therapeutic target for an aggressive form of pediatric glioma.
ECCO2017: New data reveal efficacy of pembrolizumab in further tumor types
New clinical trial data indicates that pembrolizumab immunotherapy both significantly increases survival in bladder cancer and has activity against mucosal melanoma.
Antigen-directed therapies: an effective tool in acute myeloid leukemia?
This opinion article from Immunotherapy looks at how antigen-directed therapies could hold potential for the treatment of acute myeloid leukemia and the challenges of their use to date.