Novel drug-screening technique could help identify effective cancer therapies in mice

A novel drug screening technique developed by researchers at Dana-Farber Cancer Institute (MA, USA) utilizes freshly obtained tumor samples to identify potential cancer therapies. It is hoped that the findings – published recently in Science Signaling – could result in more accurate drug screening, which in turn could lead to effective personalized treatment plans for cancer patients. Traditional drug-screening approaches use cell cultures that in some cases are years old; these static models often fail to capture the dynamic tumor microenvironment. “Cancer cells that are cultured for extended periods of time can undergo a variety of changes and may not...

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