Epigenetic regulator implicated in the persistence of Kaposi’s sarcoma-associated herpesvirus

Recent research from Instituto de Medicina Molecular João Lobo Antunes (IMM; Lisbon, Portugal) has identified a region of viral protein that is a key driver of the persistence of infection of Kaposi's sarcoma-associated herpesvirus. They also highlight epigenetic regulation as a key therapeutic avenue that could be explored for future treatments. Kaposi's sarcoma-associated herpesvirus is one of the seven known viruses that cause cancer, with infection leading to immunosuppression and Kaposi’s sarcoma in humans. No specific therapies exist for these tumors and prognosis is often poor; however, post-translational modification of a key viral protein could be a viable target for...