Are testosterone levels associated with risk of cancers?

Written by Heather Jones, Future Science Group

Research from the University of Cambridge and the University of Exeter (both UK) has revealed that genetically higher testosterone levels could increase the risk of breast and endometrial cancers in women, and prostate cancer in men. Published in Nature Medicine, this is the largest study to date on the genetic regulation of sex hormone levels and demonstrates that the genetic factors associated with testosterone levels differ greatly between the sexes. The researchers used genome wide association studies from 425,097 UK Biobank participants in order to analyze the genetic variations associated with differences in levels of testosterone and its binding protein...

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