A team of scientists have bound gene editing CRISPR/Cas9 to nucleotide aptamers to selectively target and edit osteosarcoma cancer cells.
A new genetic test could help diagnose esophageal cancer up to 8 years before symptoms appear in individuals at a high risk of the disease.
Three single-nucleotide polymorphisms have been identified as viable candidates as biomarkers for the personalized monitoring and treatment of lung cancers.
Researchers from the University of Georgia (GA, USA) have suggested the cause behind an increase in breast cancer genetic testing in the US in 2013.
In a major international collaboration, researchers have discovered 72 new genetic variants that contribute to the risk of developing breast cancer.
The largest genomics study of chordoma to date has discovered a gene mutation possessed by some patients which is a target for existing drugs known as PI3K inhibitors. Previously, these drugs have not been considered for chordoma.
Researchers from the University of Southern California Roski Eye Institute (CA, USA) have derived genetic information from retinoblastoma tumors without removing the eye.
Researchers at Sanford-Burnham Prebys Medical Discovery Institute (CA, USA) demonstrate that changes in alternative splicing are implicated in cancer.
A novel syndrome in the FANCM gene caused by biallelic mutations predisposes the body to tumors and rejection to chemotherapy.
Genome-wide methylation analysis of DNMT3B gene isoforms revealed specific methylation profiles in breast cell lines
What pathways modulated by DNMT3B isoforms and which could regulate cell proliferation and other biological mechanisms in breast cancer cell lines? Find out, in this research article from Epigenomics.