Latest News
A recent study lead by researchers at Massachusetts General Hospital (MA, USA) has highlighted a novel mechanism behind resistance to angiogenesis inhibitors.
Researchers have discovered the ability of cancer cells to force the fibroblasts in a tumor to mimic a viral infection, allowing tumors to spread and respond to attack with greater efficacy.
Researchers have demonstrated a previously undefined role of histone deacetylase 11 (HDAC11), in regulating T-cell effector functions.
Journal Articles
In this article, the authors provide an up-to-date review of all reported genomic aberrations in the eight most common pediatric solid tumors with whole-exome sequencing or whole-genome sequencing data.
This prospective, noninterventional study evaluates the effectiveness, tolerability, safety and quality of life following 450 patients with mRCC starting either on pazopanib as first-line therapy or third-line everolimus plus/minus lenvatinib following nivolumab.
This paper provides an analytical validation for the 12-gene molecular assay. This test provides a clinical score that combines molecular information from genes within the tumor with clinical information to determine whether a breast cancer is at high or low risk of recurrence.
Brain and neurologic
Role of cellular prion protein in neurofibromatosis 2 tumor development uncovered
Neuroblastoma detected by novel biomarker assay with increased sensitivity
Advancing immunotherapy for high-risk neuroblastoma patients: an interview with Juliet Gray
Breast
Novel tumor-targeted MRI contrast designed, based on human proteins
Adipose tissue may reduce radiotherapy efficacy in breast cancer patients
Colorectal
Defining a strategy for oligometastic rectal cancer: an interview with Dirk Arnold
ASCO17: Global study sets risk-based standard for chemotherapy for colon cancer
Genetic test could identify individuals at high-risk of anal cancer
Endocrine
Sonogram scoring system developed for thyroid nodules to reduce biopsy rates
Low survival rates observed for specific thyroid cancers following bone metastasis
Signaling pathways in medullary thyroid carcinoma: therapeutic implications
Gastrointestinal
ESMO WCGI: Molecular changes along the upper digestive tract discovered
Gallbladder cancer: results achieved and future challenges
Q&A follow up – A closer look at: diet and mouth and gastrointestinal cancers
Genitourinary
Immunotherapy for penile cancer
European Cancer Patient Coalition's 2017 pipeline - interview with Lydia Makaroff
Gynecologic
What are the long-term benefits and harms of human papillomavirus (HPV) testing?
Renovated (nondual) approach to endometrial cancer typing: endocrine and inflammatory issues
Head and neck
European Cancer Patient Coalition's 2017 pipeline - interview with Lydia Makaroff
AACR17: Immunotherapy efficacy may be influenced by the patient’s immune system
Hematologic
T-cells lacking HDAC11 enzyme may destroy tumor cells more effectively
Sanger Institute series: uncovering the genetics of cancer - an interview with George Vassiliou
Lung
ASCO17: Web-based reporting tool increases survival by up to 5 months
Pancreatic
Novel strategies on the horizon for pancreatic cancer: an interview with Philip A Philip
Could immunotherapy efficacy be enhanced by reprogramming tumor blood vessels?
European Cancer Patient Coalition's 2017 pipeline - interview with Lydia Makaroff
Prostate
Multiparametric MRI of the prostate gland: technical aspects
Rare tumors
An update on genomic-guided therapies for pediatric solid tumors
Biomarkers - making the early detection of mesothelioma more likely
Understanding sarcomas and other rare tumors: an interview with Robin Jones
Skin
Sanger Institute series: uncovering the genetics of cancer - an interview with David Adams
US Skin Cancer Screening Guidelines: Reviews and recommendations
Indoor tanning and melanoma: are gay and bisexual men more at risk?