Latest News
NICE have approved Tecentriq® (atezolizumab), for NHS patients with advanced bladder cancer who have relapsed following prior treatment.
Researchers have reported that children with incurable brain tumors could benefit from a potentially life-extending treatment, if genetic testing is utilized to personalize their therapy. This personalized treatment has previously only been used in adults.
A novel three-dimensional high-throughput screening approach allows researchers to identify inducers of a mutant KRAS selective lethal phenotype.
Journal Articles
In this review article find out which treatment plan is most appropriate for different groups of acute lymphoblastic leukemia patients.
This article describes a mathematical modeling framework to facilitate the prediction of clinical efficacy and toxicity of investigational antineoplastic agents.
Find out the key features of the breast tumor microenvironment as well as putative predictive biomarkers established in other tumor types. Insights from both fields could guide future studies to enable personalized breast cancer immunotherapy.
Brain and neurologic
Children with incurable brain tumors could benefit from adult therapy
Scientific and regulatory challenges in development of CAR-T therapy for solid tumors
Breast
Cause of resistance to olaparib and other PARP inhibitors identified
TAILORx: the largest ever adjuvant breast cancer treatment trial – the story so far and what’s next
Genetic test may lead to more effective chemotherapy for triple-negative breast cancer
Colorectal
Genetic fingerprints of every bowel cancer cell and bowel tumor revealed in novel study
Small, daily dose of Viagra may reduce colorectal cancer risk
Endocrine
Nivolumab + ipilimumab combo approved as first-line treatment for advanced renal cell carcinoma
Born to be bad: researchers identify the genetic roots of ‘killer' kidney cancers
Cyramza® meets primary endpoint of overall survival in liver cancer study
Gastrointestinal
New blood test could detect eight types of cancer
Study links NF1 mutations to GIST tumors, highlighting the need for genetic testing
Genitourinary
NICE approves atezolizumab for advanced bladder cancer patients on the NHS
Breakthrough method to diagnose prostate cancer developed
Researchers uncover 80 potential ways of targeting prostate cancer
Gynecologic
Cause of resistance to olaparib and other PARP inhibitors identified
Case report - Pembrolizumab in recurrent advanced cervical squamous carcinoma
Head and neck
New test could diagnose esophageal cancer 8 years before symptoms appear
Novel liquid biopsy shows promise for early retinoblastoma diagnosis
Head and neck cancer: is there a future for combination immunotherapy?
Hematologic
Management of older adults with acute lymphoblastic leukemia: challenges & current approaches
Scientific and regulatory challenges in development of CAR-T therapy for solid tumors
Lung
AACR 2018 lung cancer advancements: how will the findings translate in clinic?
Cutting-edge minimally invasive treatment shows promise for lung cancer patients
Pancreatic
Smartphone app shows promise for pancreatic cancer detection
Will gemcitabine monotherapy be dethroned as the adjuvant chemotherapy in pancreatic adenocarcinoma?
Prostate
Prostate cancer deaths are not prevented by one-off PSA screening
‘Breakthrough’ prostate cancer test could cut diagnosis time from weeks to days
Breakaway cancerous cells successfully mapped and tracked with metal detection
Rare tumors
First-in-world robot-assisted spinal surgery performed
Larotrectinib shows 93% response rate in pediatric cancer trial
Skin
AACR 2018: highlights and the biggest news headlines
AACR 2018: Positive data announced for KEYTRUDA® in adjuvant melanoma
