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Afatinib in NSCLC with uncommon EGFR mutations

Written by James Chih-Hsin Yang

The latest Publication Perspective from the Video Journal of Biomedicine summarizes a recent article published in the Journal of Thoracic Oncology, ‘Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations: A Database of 693 Cases’.

The authors analyze the effect of afatinib treatment in 693 patients with non-small-cell lung cancer (NSCLC) haboring uncommon EGFR mutations. The results provide important information when considering optimal treatment for tumors with uncommon EGFR mutations, including compound mutations.

Original publication:

Yang JCH, Schuler M, Popat S et al. Afatinib for the treatment of NSCLC harboring uncommon EGFR mutations: A database of 693 cases. J. Thorac. Oncol. 15(5), 803–815 (2020) DOI: 10.1016/j.jtho.2019.12.126

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