Our partner journal Melanoma Management has recently published a Case Report exploring electrochemotherapy for the treatment of lymph node melanoma compared with vemurafenib alone.
Abstract
Despite the progress in immunotherapy and targeted therapy for patients with cutaneous malignant melanoma not all patients with loco-regional recurrences will respond to treatment. Electrochemotherapy is a relatively new treatment modality where the efficacy of a chemotherapeutic drug is enhanced by an electrical field. Here we report a case of a 68-year-old woman with a large therapy resistant inguinal lymph node melanoma metastasis complicated by bleeding that was successfully treated with electrochemotherapy.
Read the article here
Practice points
-
Not all melanoma patients respond to targeted therapy/immunotherapy.
-
Electrochemotherapy (ECT) is a local chemotherapy treatment.
-
In ECT the effect of the chemotherapeutic drug is enhanced by an electrical field.
-
One of the effects of ECT is an antivascular effect.
-
A patient with a bleeding melanoma metastasis was successfully treated with ECT.
-
Previous treatment with BRAF inhibitor had been unsuccessful.
-
The effect was probably due to combination of ECT and BRAF inhibitor.
