Stem cell-based vaccine provides novel tactic for pancreatic cancer treatment

Researchers from International Society for Stem Cell Research (IL, USA) and Stanford University (CA, USA) have produced a cancer vaccine treatment utilizing induced pluripotent stem cells (iPSCs) in mice to train the immune system to effectively recognize cancer cells and prevent tumor development. Published in Stem Cell Reports, the researchers capitalized on the knowledge that iPSCs express antigens that are also found on different types of tumors, but not present in most normal tissue and that these antigens can be targeted for potential clinical benefit. Vaccines against cancer are still in the early stages and it has been a challenge...