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Sociodemographic disparities in treatment and survival of small localized renal cell carcinoma: surgical resection versus thermal ablation


Aim: To investigate national practice trends in the use of surgical resection (SX) versus thermal ablation (TA) for the management of T1aN0M0 renal cell carcinoma with regard to sociodemographic factors and associated outcomes. Materials & methods: Patients diagnosed in 2004–2011 were identified using the Surveillance, Epidemiology and End Results registry. Sociodemographic factors predicting the use of surgery versus TA were determined using logistic regression. Cancer-specific survival was estimated using Kaplan–Meier method. Results: Overall, 19,136 (92.9%) patients underwent SX versus 1468 (7.1%) TA. Patients who were unmarried, diagnosed between 2008 and 2011, Caucasian, aged ≥70 years, insured, residing in Pacific Coast and Northern Plains, and in metropolitan areas with higher median family income had higher likelihoods of undergoing TA. Age-adjusted cancer-specific survival was similar in the two groups. Conclusion: Despite similar survival outcomes between SX versus TA, management of T1a renal cell carcinoma lesions may be influenced by a variety of nonclinical sociodemographic factors.

Click here to view the full article in the Journal of Comparative Effectiveness Research.