Precision oncology: a clinical and patient perspective

Growing interest in identifying and characterizing genomic biomarkers has led to a paradigm shift away from non-specific cytotoxic treatment strategies, toward personalized treatment strategies based on the genomic profile of a tumor. This review article from Future Oncology provides an overview of the current status of precision oncology and what is needed to integrate molecular profiling into the advanced cancer patient journey. Abstract Molecular characterization of tumors has shifted cancer treatment strategies away from nonspecific cytotoxic treatment of histology-specific tumors toward targeting of actionable mutations that can be found across multiple cancer types. The development of high-throughput technologies such as...