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Precision medicine oncology: what are the major challenges?

Written by Rachel Jenkins, Senior Editor

Precision medicine in oncology can be broadly defined as tailored cancer therapy based on an individual patient’s genetic make-up [1]. Over recent years, the development and utilization of precision medicine in healthcare has been accelerated. For example, the establishment of next generation sequencing has enabled genomic characterization of patients and the creation of shared genomic databases. Large-scale sequencing programs such as the All of Us Research Program (NIH, MD, USA) and the 100,000 Genomes Project (NIHR, UK) have been set up [2,3]. The aim of these programs is to collect genetic and health data to advance medicine. Despite this potential,...

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