Loss of Y chromosome drives cancer growth in males with bladder cancer

It has long been recognized that somatic cells in men occasionally lose the Y chromosome and this occurrence increases with chronological age. Scientists have linked this loss of chromosome Y (LOY) to a list of diseases including Alzheimer’s Disease and heart failure. New research has reported that LOY could have important implications in cancer, specifically a form of aggressive bladder cancer. Dan Theoforescu, director of the Cedars-Sinai Cancer (CA, USA), the PHASE ONE Distinguished Chair and corresponding author of the publication commented, “this study for the first time makes a connection that has never been made before between loss of...