Leukemia drugs could be used against treatment-resistant lung cancer

Written by Heather Jones, Future Science Group

Researchers from the University of Toronto (Canada) have discovered two recently approved leukemia drugs that could also be effective against treatment-resistant lung cancer. The study, published in Nature Chemical Biology, used a novel live cell-based method to identify small molecules that target specific mutations in cancer cells. Lung cancer accounts for a high number of mortalities worldwide. Non-small cell lung cancer is the most common type of the disease, with approximately one-fifth of cases in North America caused by mutations in the receptor tyrosine kinase, epidermal growth factor receptor (EGFR). Although dozens of kinase inhibitors have been used that target...

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