Leukemia drugs could be used against treatment-resistant lung cancer

Researchers from the University of Toronto (Canada) have discovered two recently approved leukemia drugs that could also be effective against treatment-resistant lung cancer. The study, published in Nature Chemical Biology, used a novel live cell-based method to identify small molecules that target specific mutations in cancer cells.Lung cancer accounts for a high number of mortalities worldwide. Non-small cell lung cancer is the most common type of the disease, with approximately one-fifth of cases in North America caused by mutations in the receptor tyrosine kinase, epidermal growth factor receptor (EGFR). Although dozens of kinase inhibitors have been used that target specific...