Cancer epigenetic therapy: recent advances, challenges, and emerging opportunities

Epigenetic dysregulation, as a result of alterations in epigenetic regulators, is a fundamental feature of many cancers. Research into cancer-specific mechanisms that lead to epigenetic dysregulation has been conducted over many years, resulting in significant progress in the field of drug discovery. This review article from Epigenetics discusses epigenetic dysregulation in cancer and the emerging opportunities, advances and challenges in developing cancer epigenetic therapies.