CAR-T cells can be controlled by light to target skin tumors in mice

Written by Heather Jones, Future Science Group

Bioengineers from the University of California San Diego (CA, USA) have developed a novel method using light, designed to control the targeting of CAR-T cells. The study is published in Science Advances and reports the results of testing the system on mice with skin tumors. The system could potentially make CAR-T therapy safer and more powerful when treating cancer. CAR-T therapy allows a more tailored approach to cancer therapy as it involves genetically engineering a patient’s T cells to target cancer cells. This approach has so far worked well for some blood cancers, however, it is yet to prove effective...

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