NCCTG N0574 (Alliance): Phase III study of whole brain radiation therapy in addition to radiosurgery in patients with 1 to 3 brain metastases

In this short presentation, filmed at the 2015 Annual Meeting of the American Society for Clinical Oncology, Jan Buckner of Mayo Clinic (MN, USA) summarizes the key findings of the Alliance trial. Presented in the Plenary Session of the ASCO meeting, the trial indicated that whole brain radiation therapy did not improve overall survival in this patient population, but increased cognitive decline.