Researchers have discovered that anti-PD-1/PD-L1 therapies are highly effective in patients with desmoplastic melanoma, challenging previous assumptions.
Browsing: tumor biology
Find out about the characteristics of patient-derived xenograft models and their application for basic & preclinical cancer research in this editorial from Future Science OA.
Scientists have revealed that a human protein – identified as YTHDF2 – could prevent cancer by restricting the human herpes virus 8, otherwise known as Kaposi’s sarcoma-associated herpesvirus.
Researchers at the Ludwig Institute for Cancer Research (Brussels, Belgium) have discovered a novel mechanism used by tumors to evade immunotherapies.
A team of researchers have reported T cells survive a tumor’s anoxic environment and become more effective at killing cancer cells by exploiting HIF-1a and when they have access to growth factor VEGF-A.
Circumvent hesitancy between CDK4/6 and mTOR inhibitors in second-line treatment of HR+, erb2- metastatic breast cancer
In this editorial from Future Oncology the authors explore tumor biology, host biology and patient’s quality of life in respect to circumvent hesitancy between CDK4/6 and mTOR inhibitors in second-line treatment of HR+, erb2- metastatic breast cancer.
A novel study has demonstrated how the Warburg effect, a phenomenon in which cancer cells rapidly breaks down sugars, stimulates tumor growth
Researchers have discovered that lung cancer cells are able to utilize lactate as an energy source to facilitate growing. This finding challenges the previous understanding of cancer metabolism and may have implications for future cancer research.
A study has demonstrated the inhibitory effects of damsin – found in Ambrosia arborscens – on breast cancer stem cells. Ambrosin, a synthetically produced compound similar to damsin also has the same anti-cancer capabilities.
Researchers at Sanford-Burnham Prebys Medical Discovery Institute (CA, USA) demonstrate that changes in alternative splicing are implicated in cancer.