This editorial discusses the effectiveness of targeting hormone receptors in the management of adrenal hyperplasia.
HER2/neu: an increasingly important therapeutic target. Part 1: basic biology & therapeutic armamentarium
This review will summarise the pertinent biology of HER2/neu and the EGF receptor family to which it belongs.
Researchers from the University of Michigan (MI, USA) have discovered in mice a new protein termed galectin-1, which may allow high-grade gliomas to go undetected by the host’s immune system.
This article discusses the potential use of ERG expression as a diagnostic biomarker for prostate cancer and highlights a possibility that it may have limited utility for African-American men compared to European-American men.
Results reported online yesterday in Cell Reports discuss the identification of a genetic network that may fuel certain aggressive cases of acute myeloid leukemia (AML), as well as its precursor disease myelodysplastic syndrome (MDS).
Targeting antiapoptotic and proapoptotic proteins for novel chronic lymphocytic leukemia therapeutics
This review discusses a number of studies which have utilised methods such as the inhibition of prosurvival factors or upregulation of proapoptotic proteins in order to treat CLL.
A recent study from the University of California, San Diego School of Medicine (CA, USA) has reported that dietary capsaicin, the active ingredient in chilli peppers, can potentially reduce the risk of colorectal tumors.
A recent study conducted by researchers at the Cancer Research UK Beatson Institute (Glasgow, UK) and the University of Glasgow, has highlighted the potential in using the genetic signatures of human pancreatic tumors to direct cancer treatment.