Research has demonstrated that ovarian cancer patients with a tumor mutation in the BRAF gene respond exceptionally well to BRAF inhibitors.
Browsing: cell signaling
To mark International Women’s Day we recently spoke with Victoria Sanz Moreno from Kings College London (UK) to find out what inspired her to get into cancer research.
Scientists have revealed that a human protein – identified as YTHDF2 – could prevent cancer by restricting the human herpes virus 8, otherwise known as Kaposi’s sarcoma-associated herpesvirus.
Circumvent hesitancy between CDK4/6 and mTOR inhibitors in second-line treatment of HR+, erb2- metastatic breast cancer
In this editorial from Future Oncology the authors explore tumor biology, host biology and patient’s quality of life in respect to circumvent hesitancy between CDK4/6 and mTOR inhibitors in second-line treatment of HR+, erb2- metastatic breast cancer.
Research into the PD-L1 pathway has discovered a novel protein known as CMTM6, which binds to PD-L1 on T cell surfaces and enhances PD-L1’s ability to inhibit T cell immune responses. The findings may offer a novel immunotherapy target for many types of cancer.
Researchers at Sanford Burnham Prebys Medical Discovery Institute (CA, USA) have published a study shedding new light on how the anti-cancer agent K-80003 (TX803) inhibits cancer cell growth.
Researchers have shed light on the mechanism by which cyclooxygenase-2 expression potentially drives immune suppression in tumors.
Researchers have discovered the ability of cancer cells to force the fibroblasts in a tumor to mimic a viral infection, allowing tumors to spread and respond to attack with greater efficacy.
Researchers have discovered a potential new method of stopping metastasis by simultaneously inhibiting IL-6 and IL-8 paracrine signalling pathways.
Researchers have demonstrated that IL-6 controls resistance to radiation in oral squamous cell carcinoma.