Could necroptotic cells induce tumor clearance?

Researchers from the University of Washington (WA, US) and Rutgers University in Piscataway (NJ, US) have collaborated to produce a novel technique which promotes the immune system to attack tumors. Their method involves injecting engineered dying cells directly into a tumor that activates the immune system into clearance of tumors both at the administration site and distal sites. Research into the use of necroptosis pathways in tumor immunology has been limited due to the difficulty of triggering specific cell death programs in live animals. However, recent studies have built growing evidence that necroptosis could be used to activate and suppress...