Analyzing immune responses of hematological cancers could inform immunotherapy options

A multi-institute team including researchers from the University of Eastern Finland, the University of Helsinki and Helsinki University Hospital (all Finland) have utilized a dataset comprising over 10,000 patients to characterize the immune landscape of hematological cancers. It is hoped the work – published this week in Cancer Cell – could be used to identify effective immunotherapies and stratify patients who are more likely to respond to immunotherapy.Immunotherapy has shown particular promise for the treatment of solid tumors; however, its potential in hematological malignancies is yet to be fully realized. Immunotherapy works by activating the immune system in an attempt...