Philippe Lambin speaks to Alisa Crisp, Commissioning Editor: Philippe Lambin is a clinician, a radiation oncologist, and a pioneer in translational research with a focus on hypoxia and Decision Support Systems. He has a PhD in radiation biology and is professor at the University of Maastricht (radiation oncology) and at the University of Eindhoven (functional imaging). He is co-author of more than 282 peer-reviewed scientific papers (Hirsch Index: 42), co-inventor of more than 13 patents (filed or submitted) and (co)promotor of more then 27 completed PhDs. Moreover, Professor Lambin has extensive experience with clinical trials. He is one of the international experts in the Flims workshop ‘Methods in Clinical Cancer Research’ organized jointly by the Federation of European Cancer Societies, American Association for Cancer Research and American Society of Clinical Oncology and he is leading several clinical trials. He is also a member of the scientific committee of Koningin Wilhelmina Fonds (the main Dutch funding body in cancer research) and the advice committee on proton therapy of College Voor Zorgverzekeringen (Dutch medical insurance). He is currently involved in several successful European grants (e.g., Centre for Disruptive Photonic Technologies, Biocare, Euroxy, Metoxia, euroCAT and Eureca) and one NIH grant (in radiomics). His main areas of interest are directed towards translational research in radiation biology with a specific focus on tumor hypoxia, functional imaging (computed tomography–PET) and lung and head and neck cancer.