Jenny Chang-Claude speaks to Marco De Ambrogi, Commissioning Editor: Jenny Chang-Claude is Head of the Unit of Genetic Epidemiology in the Division of Cancer Epidemiology and also is the Deputy Head of the Division of Cancer Epidemiology at the German Cancer Research Center (Heidelberg, Germany). Since 2004 she has been Professor in Epidemiology at the University of Heidelberg (Heidelberg, Germany). Chang-Claude has one of the leading research groups in genetic epidemiology of breast cancer in Germany, with collaborations both nationally and internationally. She has conducted multicenter case–control studies and cohort follow-up studies in Germany, with a research focus on the identification of lifestyle and genetic determinants for risk and prognosis of breast and colorectal cancer, and gene–environmental interactions. Additional research includes studies on cancer survivorship and radiosensitivity. She is also actively involved in research activities of international consortia on breast, ovarian and colorectal cancer. Chang-Claude serves on international scientific advisory boards, committees and editorial boards. She is a (co)author of more than 350 scientific papers published in international scientific journals.