An increasing number of breast cancer survivors have been using acupuncture to reduce side effects associated with cancer treatment, such as joint/muscle discomfort, hot flashes, lymphedema, fatigue, chemotherapy-induced peripheral neuropathy, anxiety and depression. Rigorous clinical research has begun to investigate the safety, efficacy of acupuncture in treating such conditions. Acupuncture has been shown to be a safe procedure with minimal side effects. Most studies showed that acupuncture is significantly better than no acupuncture in relieving such symptoms. The benefit of real acupuncture over sham acupuncture in treating such symptoms has not been fully established. Additional research is needed to determine the efficacy, mechanism and cost–effectiveness of acupuncture. Meanwhile, since acupuncture poses minimal risks and carries potentially significant benefits, this medical procedure remains a reasonable treatment option for breast cancer survivors to alleviate cancer treatment induced side effects.