The European Commission has recently approved dinutuximab beta for high risk neuroblastoma patients over the age of 12 months, making it the only approved immunotherapy in Europe for this group of patients.
Brain and neurologic
This paper provides an analytical validation for the 12-gene molecular assay. This test provides a clinical score that combines molecular information from genes within the tumor with clinical information to determine whether a breast cancer is at high or low risk of recurrence.
Listen to this exclusive interview with Dirk Arnold from Klinik für Tumorbiologie (Freiburg, Germany) about current treatment options for rectal cancer, how we can define a strategy for oligometastic rectal cancer and his hopes for the future of this field.
Explore the role of epigenetics in neuroendocrine prostate cancer in this peer-reviewed article from Epigenomics.
The expert speakers from our recent webinar on the links between diet and mouth and gastrointestinal cancers address further questions from our audience.
This article reviews progress made in the creation of a transplantable artificial ovary and discusses future trends for its development.
Head and neck
For head and neck cancer, saliva represents a diagnostic medium of notable advantages, especially as it is in close proximity to the disease. This review looks into the two common epigenetic alterations and their potential clinical utility.
In this interview find out about Anthony Nolan’s research strategy, breakthroughs that have aided the advancement of stem cell transplantation, how third-generation sequencing for HLA typing may improve donor-recipient matching and the direction that Alejandro Madrigal envisions Anthony Nolan’s research will take in the coming years.
Available to view on demand
Learn about a study that was accomplished as a means to explore the hypothesis that circulating concentrations of decoy receptors and/or ligands, as well as disease-specific ligand degradation all regulate RTK signaling in vivo.
Listen to our exclusive interview with Philip A Philip to find out about novel agents and strategies on the horizon for pancreatic cancer.
Prostate cancer screening and detection remain challenging issues, with changes in recommendations for prostate-specific antigen testing causing a significant change in approach. In this editorial discover the multiple roles and applications of prostate MRI.
Editor, Jade Parker recently spoke with world-renowned sarcoma expert, Robin L Jones. In this interview discover challenges in the diagnosis, treatment and clinical trials of sarcoma and other rare tumors.
In this infographic gain a visual snapshot of a review article in which over 50 leaders in the dermatology field critically assess current screening practice for melanoma in an effort to propose rational, risk-based, data-driven guidelines for skin cancer screening.