Patients with rare cancers who are not able to receive standard treatment may be able to receive existing therapies designed for different cancers with the same genetic mutations, according to a novel study.
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A recent study published in JCO Precision Oncology provides new insights into the pathobiology of NF1 mutant GISTs. Demonstrating the potential of genomically driven precision oncology care in the implementation of personalized treatments and counselling for patients with GISTs.
Researchers have demonstrated the promise of quantitative whole genome sequencing of circulating tumor cells in enabling personalized combination therapy of metastatic cancer.
This paper reviews genetic variations mainly related to the onset of adverse events during aromatase inhibitors in early breast cancer.
New research looking at childhood cancer survivors has suggested that radiation therapy could trigger genomic structural rearrangements, providing a genetic basis for meningioma later in life.
In this review, gaps and limitations in pharmacogenomics in pediatric acute lymphoblastic leukemia are emphasized, which may provide a useful guide for future research design.
Researchers have unveiled the first draft of a genome-wide cancer ‘dependency map’; the map reveals more than 760 genetic dependencies across multiple cancers.
In this interview, Illumina’s Chief Scientist, David Bentley, speaks about the 100,000 Genomes Project which could transform the way cancer patients are cared for.
Researchers have highlighted the potential of liquid biopsy’s ability to further our understanding of why in some individuals, cancer treatments lose effectiveness.
Researchers have unearthed molecular changes along the digestive tract that could aid the development of targeted therapies.