Oncology Central

Adjuvant chemotherapy and follow-up for recurrences in localized testicular cancer

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Patients diagnosed with testicular germ cell tumor (seminoma and nonseminomatous germ cell tumor [NSGCT]) have one of the best prognoses of malignant neoplasms [1]. Following orchiectomy for stage I (testis confined) disease, management options include adjuvant chemotherapy and active surveillance. Although chemotherapy is associated with lower risk of relapse compared with surveillance, the long-term survival is excellent in both cases given the tumor’s exquisite sensitivity to cytotoxic drugs, particularly to bleomycin, etoposide and cisplatin (BEP).

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