Original Publication Date: 1 August, 2016
Publication / Source: Immunotherapy
Authors: Xiaomin Fu ‡ , Yong Zhang ‡ , Quanli Gao et al.
Idiopathic thrombocytopenic purpura (ITP) is characterized by a diminished platelet count, an autoimmune condition with antibodies against platelets and an increased tendency to bleed. The association between ITP and solid tumors is uncommon. Cytokine-induced killer (CIK) cell therapy is a well tolerated and promising cancer treatment with minimal toxicity. For the first time, CIK cell therapy was reported to be followed by ITP. The mechanism through which CIK induces ITP remains unclear.