Original Publication Date: 1 June, 2017
Publication / Source: Pharmacogenomics
Authors: Matthew Goblirsch, Georg Richtig, Ondrej Slaby, Ioana Berindan-Neagoe, Armin Gerger & Martin Pichler
Colorectal cancer is a common type of malignant disease with high rates of morbidity and mortality. Although treatment options have been expanded over the last years, the mainstay of curative treatment remains surgical removal of the tumor-bearing organ. Systemic treatment options include classic cytotoxic drugs as well as some biological agents. Noncoding RNAs are an evolving field in cancer diagnosis, prognosis and possible treatment. Noncoding miRNAs are small molecules with huge impact on gene expression.