Original Publication Date: 1 March, 2017
Publication / Source: Immunotherapy
Authors: Alireza Bolourian & Zahra Mojtahedi
Natural killer (NK) cells target the cells losing MHC-I in cancer, a phenotype that is similar to certain cells in immune-privileged sites whose milieus are separated from peripheral blood. NK cells are reported to be quantitatively and qualitatively different in immune-privileged sites from those cytotoxic ones in the blood.