Original Publication Date: 1 January, 2017
Publication / Source: Future Oncology
Authors: Theresa M Kolben, Franziska Kraft, Thomas Kolben et al
Aim: Cervical intraepithelial neoplasia (CIN) is commonly divided into three grades. Guidelines increasingly recommend surgery only in CIN 3 lesions. We investigated markers to evaluate differences in CIN 2 and 3 lesions as well as possible predictors for regression/progression in CIN 2 lesions. Materials & methods: Biopsies (n = 128) of healthy cervical tissue and CIN 1–3 were stained for Sialyl Lewis a, Sialyl Lewis x, Lewis y, Gal-3, Gal-7, STMN1 and p16.