Oncology Central

Proton therapy for pediatric cancer: are we ready for prime time?


The majority of pediatric oncology patients become long-term survivors who must live with the effects of their diseases and treatments for many decades [1]. Although there is a trend toward reduced use of radiation therapy in children with cancer, it continues to play an essential role in the treatment of many common pediatric malignancies, including brain tumors, sarcomas, lymphomas and neuroblastoma [2]. Therefore, it is imperative to deliver effective radiation therapy with the least morbidity possible in the treatment of children with cancer. Proton beam therapy (PBT) is promising for its potential to provide equivalent efficacy in treating pediatric cancer patients with improved acute and late side-effect profiles due to the lack of exit dose from its beams.

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