Original Publication Date: 1 October, 2016
Publication / Source: Future Oncology
Authors: Jose Augusto Monteiro de Oliveira Novaes & William N William Jr
Oral squamous cell carcinomas represent a significant cancer burden worldwide. Unfortunately, chemoprevention strategies investigated to date have failed to produce an agent considered standard of care to prevent oral cancers. Nonetheless, recent advances in clinical trial design may streamline drug development in this setting. In this manuscript, we review some of these improvements, including risk prediction tools based on molecular markers that help select patients most suitable for chemoprevention.