Original Publication Date: 1 September, 2016
Publication / Source: Melanoma Management
Authors: Ricardo Moreno-Traspas, Igor Vujic, Martina Sanlorenzo & Susana Ortiz-Urda
Melanoma is one of the leading cancers worldwide, distinguished for its malignancy and low survival rates. Although the poor outcome could improve with an early diagnosis and a good monitoring of the disease, current melanoma biomarkers display several limitations which make them useless. Interestingly, long-noncoding RNAs are secreted into the bloodstream inside exosomes by a wide range of malignant cells, and several of them have been validated as promising circulating molecular signatures of other tumors, but not melanoma.