Oncology Central

The potential of mesenchymal stromal cells in immunotherapy


Over the past years, extensive studies have been conducted to develop safe and effective therapeutic strategies to treat human diseases. Immunomodulation refers to the manipulation of the immune system either by enhancing (immunopotentiation strategy), or supressing (immunosuppression strategy) the immune responses. Immunomodulation can be achieved by different agents, referred to as immunomodulators, including monoclonal antibodies, cytokines, glucocorticoids, adjuvants, ultraviolet light, plasmapheresis and many others [1]. Mesenchymal stromal cells (MSCs) are immunomodulators of special interest and have been suggested as promising therapeutics for several autoimmune diseases and transplantation complications [2].

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