Original Publication Date: 1 February, 2016
Publication / Source: Nanomedicine
Authors: Petra Gener, Diana Fernandes de Sousa Rafael, Yolanda Fernández et al
Despite the progress in cancer treatment over the past years advanced cancer is still an incurable disease. Special attention is pointed toward cancer stem cell (CSC)-targeted therapies, because this minor cell population is responsible for the treatment resistance, metastatic growth and tumor recurrence. The recently described CSC dynamic phenotype and interconversion model of cancer growth hamper even more the possible success of current cancer treatments in advanced cancer stages.