Original Publication Date: 1 March, 2016
Publication / Source: Biomarkers in Medicine
Authors: Yenkai Lim, Charles Xiaohang Sun, Peter Tran & Chamindie Punyadeera
The early detection of head and neck squamous cell carcinoma (HNSCC) continues to be a challenge to the clinician. Saliva as a diagnostic medium carries significant advantages including its close proximity to the region of interest, ease of collection and noninvasive nature. While the identification of biomarkers continues to carry significant diagnostic and prognostic utility in HNSCC, epigenetic alterations present a novel opportunity to serve this purpose.