Oncology Central

Palbociclib: an approval at last for HER2-negative breast cancer

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In 2013, trastuzumab–emtasine conjugate (T-DM1) was approved by the US FDA for metastatic HER2-positive breast cancer. Now, a long-term expectation by patients and physicians becomes a reality for HER2-negative breast cancer. Palbociclib has recently received regulatory approval presenting a new therapeutic horizon for postmenopausal women with estrogen receptor-positive (ER+)/HER2-negative metastatic breast cancer.

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