Original Publication Date: 1 May, 2016
Publication / Source: Future Oncology
Authors: Hampig Raphael Kourie, Samer Tabchi & Joseph Kattan
Immune checkpoint inhibitors are new biologic agents currently in the process of revolutionizing cancer care. By blocking pro-inhibitory agents of the immune response, these agents allow for a restitution of the cancer-killing properties of the immune system which will no longer be limited by the tumor’s ability to evade detection. Different agents (anti-CTLA4, anti-PD-1 and anti-PD-L1) were approved in the past few years for different malignancies and in different settings.