Oncology Central

Medulloepithelioma with peculiar clinical presentation, stem cell phenotype and aberrant DNA-methylation profile

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We present a 21-year-old male with a neck mass diagnosed as medulloepithelioma. Despite aggressive chemo- and radio-therapy, the tumor metastasized and proved fatal after seventeen months. The tumor demonstrated robust immunohistochemical expression of multiple markers of embryonic/neural stem cells and embryogenesis from the paraffin embedded tissue.

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