Original Publication Date: 1 June, 2015
Publication / Source: Future Oncology
Authors: Omar Abdel-Rahman & Mona Fouad
This systematic review aims at assessment of the available evidence for systemic therapy options for patients with advanced gastrointestinal stromal tumors beyond first-line imatinib. Eligible trials were identified using databases search. In total, 26 studies were eligible and included in the final analysis. Among second-line studies, median progression-free survival ranged from 1.9 to 10 months while median overall survival ranged from 15 to 62 months.