Original Publication Date: 1 April, 2015
Publication / Source: Immunotherapy
Authors: Tracy L Putoczki & Matthias Ernst
IL-11 is a member of the IL-6 family of cytokines. While it was discovered over 20 years ago, we have very little understanding of the role of IL-11 during normal homeostasis and disease. Recently, IL-11 has gained interest for its newly recognized role in the pathogenesis of diseases that are attributed to deregulated mucosal homeostasis, including gastrointestinal cancers.