Original Publication Date: 1 April, 2015
Publication / Source: Immunotherapy
Authors: Annie Mirsoian & William J Murphy
Within the past decade the usage of cancer immunotherapy has gained momentum, achieving successes within various advanced-staged malignancies and is beginning to be explored as a primary therapeutic rather than secondary to traditional cytoreductive therapies. Immunotherapeutic antitumor approaches have included systemic stimulatory therapies, blocking checkpoint inhibitory pathways, direct induction of T-cell stimulatory pathways and adoptive cell transfer strategies, among others .