Original Publication Date: 1 January, 2015
Publication / Source: Personalized Medicine
Authors: Kristen R Dearing & Glen J Weiss
Next-generation sequencing (NGS) is being applied in oncology care to identify specific molecular aberrations of patient’s tumors. The use of NGS now allows for sequencing entire human genomes within a reasonable cost and practical time frames for treatment decision making. Further delineation of epigenetics, transcriptomics, metagenomics and NGS at the level of circulating tumor DNA reveal ever increasing complexity to understand these interactions and the roles they play in cancer.