Original Publication Date: 1 December, 2014
Publication / Source: Future Oncology
Authors: Alberto Bongiovanni, Marianna Ricci, Nada Riva et al.
Gastrointestinal stromal tumors are rare malignancies characterized by c-kit and PDGFR-α mutations targeted by imatinib. Pleural effusion is a very rare side effect of imatinib treatment. A 65-year-old female with metastatic gastrointestinal stromal tumor developed electrolyte imbalance, severe peripheral edema and progressively worsening dyspnea 2 months after starting imatinib.