Original Publication Date: 1 October, 2014
Publication / Source: Future Oncology
Authors: Aneta Pichler, Martin Pichler
Cancer is a complex disease and the diagnosis of this commonly life-threatening illness is associated with fundamentally physical and psychological strains. In the last decade, there has been major progress in understanding the molecular and cellular pathways that are altered in several types of cancer. Currently, there are strong technological efforts to elucidate the role of diverse pathophysiological factors including but not restricted to cancer stem cells , miRNAs , mutations or single nucleotide polymorphism , and whole genome sequencing of circulating tumor DNA . Overall, most oncologists and clinical researchers follow the encouraged major aims: to improve the diagnosis, prognosis and therapy of cancer.